A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia - ScienceDirect
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Descrição
Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-ba…
Synergistic targeting of FLT3 mutations in AML via combined menin
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
Transcription factor abnormalities in B-ALL leukemogenesis and
A Menin-MLL Inhibitor Induces Specific Chromatin Changes and
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
Epigenetic deregulation in myeloid malignancies - ScienceDirect
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
MLL::AF9 degradation induces rapid changes in transcriptional
Disordered epigenetic regulation in MLL-related leukemia
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