2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
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Descrição
Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
Frontiers Causes and Consequences of Flavivirus RNA Methylation
IFIT1: A dual sensor and effector molecule that detects non-2'-O methylated viral RNA and inhibits its translation. - Abstract - Europe PMC
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Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals
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Specific interaction of IFIT1 and IFIT1B with the 5′-terminal regions
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2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo
Attenuation of SARS‐CoV‐2 replication and associated inflammation by concomitant targeting of viral and host cap 2'‐O‐ribose methyltransferases
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